Will your protein fit inside ferritin?

enCAGE estimates how compatible your protein is with apoferritin encapsulation using experimentally derived structural descriptors.

Upload a PDB file, ID enter a PDB ID, or try one of our example proteins to get started.

Size & Shape Evaluates whether your protein can physically fit within the ferritin cavity.

Surface Charge Assesses electrostatic compatibility with the negatively charged interior of ferritin.

Prediction Engine Applies experimentally derived rules to predict the most likely encapsulation outcome.

Instant Analysis No installation required. Analyse protein structures directly in your browser.

Your analysis will include

• Overall compatibility assessment
• Predicted encapsulation outcome
• Size and shape analysis
• Surface charge analysis
• Mechanistic explanation
• Downloadable report

Built on experimental evidence

enCAGE uses transparent, descriptor-guided rules derived from systematic experimental studies of apoferritin encapsulation.

No black-box scoring. Just interpretable science you can trust.